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Type 2 diabetes is causally associated with depression: a Mendelian randomization analysis

Liping Xuan, Zhiyun Zhao, Xu Jia, Yanan Hou, Tiange Wang, Mian Li, Jieli Lu, Yu Xu, Yuhong Chen, Lu Qi, Weiqing Wang, Yufang Bi, Min Xu

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 678-687 doi: 10.1007/s11684-018-0671-7

Abstract: We aimed to determine the causal relation by performing a Mendelian randomization (MR) study using 34An MR analysis was performed involving 11 506 participants from a large longitudinal study.

Keywords： causal modeling     depression     Mendelian randomization     type 2 diabetes    

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Bidirectional Causality Between Immunoglobulin G N-Glycosylation and Metabolic Traits: A Mendelian RandomizationStudy Article

Xiaoni Meng, Weijie Cao, Di Liu, Isinta Maranga Elijah, Weijia Xing, Haifeng Hou, Xizhu Xu, Manshu Song, Youxin Wang

Engineering 2023, Volume 26, Issue 7,   Pages 74-88 doi: 10.1016/j.eng.2022.11.004

Abstract: In this work, we used Mendelian randomization (MR) analysis to integrate genome-wide association studies

Keywords： Mendelian randomization study     Immunoglobulin G     N-glycosylation     Metabolic traits     Quantitative trait    

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Exome sequencing greatly expedites the progressive research of Mendelian diseases

Xuejun Zhang

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 42-57 doi: 10.1007/s11684-014-0303-9

Abstract: sequencing with linkage studies is one of the most efficient strategies in searching disease genes for MendelianWES has achieved great success in the past three years for Mendelian disease genetics and has identifiedover 150 new Mendelian disease genes.With an affordable cost, WES is expected to become the most commonly used tool for Mendelian disease

Keywords： genetics     whole-exome sequencing     Mendelian disease     disease gene    

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Scale study of sites and pavilions for World Expo 2010

ZHOU Zhuoyan, CHEN Yi

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 1,   Pages 102-106 doi: 10.1007/s11709-008-0012-z

Abstract: The scale of sites and pavilions for World Expo 2010 (Shanghai World Expo) mainly refers to the study

Keywords： pavilion     study     number     appropriate     design    

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Practicality study on air-powered vehicle

LIU Lin, YU Xiaoli

Frontiers in Energy 2008, Volume 2, Issue 1,   Pages 14-19 doi: 10.1007/s11708-008-0004-7

Abstract: To investigate the feasibility and outlook of air-powered vehicles including compressed air-powered vehicle and liquid nitrogen-powered vehicle, thermodynamic analysis and experiment data were used to analyze the energy density, performance, safety, running efficiency, fuel circulation economy and consumer acceptance, etc. The results show that compressed air and liquid nitrogen have similar energy density as Ni-H battery; the characteristics of an air-powered engine is suitable for driving a vehicle; the circulation efficiency of liquid nitrogen is 3.6%–14% and that of compressed air is 25%–32.3% in practice, and existing technology can assure its safety. It is concluded that though the performance of an air-powered engine is inferior to that of the traditional inert combustion engine, an air-powered vehicle is fit for future green cars to realize the sustainable development of society and environment.
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Experimental study on shear behavior of prestressed reactive powder concrete I-girders

Hui ZHENG, Zhi FANG, Bin CHEN

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 3,   Pages 618-627 doi: 10.1007/s11709-018-0500-8

Abstract: Further study should be needed to develop an analytical method and computation model for shear strength

Keywords： prestressed concrete     RPC(Reactive Powder Concrete)     concrete beams     shear strength     experimental study    

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A feasibility study of the measuring accuracy and capability of wireless sensor networks in tunnel monitoring

Xiaojun LI, Zhong JI, Hehua ZHU, Chen GU

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 2,   Pages 111-120 doi: 10.1007/s11709-012-0150-1

Abstract: Fire disasters and the deterioration of tunnel structures are major concerns for tunnel operation and maintenance. Traditional wired monitoring systems have many drawbacks in terms of installation time, overall cost, and flexibility in tunnel environments. In recent years, there has been growing interest in the use of wireless sensor networks (WSNs) for the monitoring of various structural monitoring applications. This paper evaluated the feasibility of applying a WSN in the monitoring of tunnels. The monitoring requirements of tunnels under explosion and combustion fire scenarios are analyzed using numerical simulation, and the maximum possible distance for temperature sensors is derived. The displacement monitoring of tunnels using an inclinometer is investigated. It is recommended that the inclinometer should be installed in the 1/4 span of the tunnel structure. The maximum wireless transmission distances in both outdoor and tunnel environments were examined. The influences of surface materials and sensor node locations on the data transmission distance in tunnel environments were also investigated. The experimental results show that the data loss in tunnel environments is approximately three times that in outdoor environments. Surface material has a considerable influence on the transmission distance of radio signals. The distance is 25 ? 28 m for a raw concrete surface, 20 m for a brick surface, and 36 m for a terrazzo surface. The transmission distances along the middle of quarter points are approximately 0.9 ( is the transmission distance in the center of the tunnel), and the relative error is less than±3%. The transmission distances at different locations along the bottom exhibit significant differences, decreasing from the middle to the corner point, with distances of approximately 0.8 at the quarter points and minimum distances of approximately 0.55 at the corner points.

Keywords： wireless sensor network (WSN)     tunnel     monitoring     feasibility study    

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Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical

Ying Ma,Nanxue Zhang,Shi Wu,Haihui Huang,Yanpei Cao

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 517-521 doi: 10.1007/s11684-016-0480-9

Abstract:

This study aimed to compare the antimicrobial activities of topical agents against Propionibacterium

Keywords： antimicrobial susceptibility/resistance     Propionibacterium acnes     topical antibiotics     in vitro study    

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Genetic study and molecular breeding for high phosphorus use efficiency in maize

Dongdong LI, Meng WANG, Xianyan KUANG, Wenxin LIU

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 4,   Pages 366-379 doi: 10.15302/J-FASE-2019278

Abstract:

Phosphorus is the second most important macronutrient after nitrogen and it has many vital functions in the life of plants. Most soils have a low available P content, which has become a key limiting factor for increasing crop production. Also, low P use efficiency (PUE) of crops in conjunction with excessive application of P fertilizers has resulted in serious environmental problems. Thus, dissecting the genetic architecture of crop PUE, mining related quantitative trait loci (QTL) and using molecular breeding methods to improve high PUE germplasm are of great significance and serve as an efficient approach for the development of sustainable agriculture. In this review, molecular and phenotypic characteristics of maize inbred lines with high PUE, related QTL and genes as well as low-P responses are summarized. Based on this, a breeding strategy applying genomic selection as the core, and integrating the existing genetic information and molecular breeding techniques is proposed for breeding high PUE maize inbred lines and hybrids.

Keywords： maize     phosphorus use efficiency     quantitative trait loci     genetic study     molecular breeding     genomic selection    

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Parametric study on seismic performance of self-centering reinforced concrete column with bottom-placed

Frontiers of Structural and Civil Engineering   Pages 1145-1162 doi: 10.1007/s11709-023-0945-2

Abstract: To realize seismic-resilient reinforced concrete (RC) moment-resisting frame structures, a novel self-centering RC column with a rubber layer placed at the bottom (SRRC column) is proposed herein. For the column, the longitudinal reinforcement dissipates seismic energy, the rubber layer allows the rocking of the column, and the unbonded prestressed tendon enables self-centering capacity. A refined finite element model of the SRRC column is developed, the effectiveness of which is validated based on experimental results. Results show that the SRRC column exhibits stable energy dissipation capacity and no strength degradation; additionally, it can significantly reduce permanent residual deformation and mitigate damage to concrete. Extensive parametric studies pertaining to SRRC columns have been conducted to investigate the critical factors affecting their seismic performance.

Keywords： seismic resilience     self-centering     rubber layer     flag-shaped hysteresis loop     parametric study    

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Experimental study on the laminar flame speed of hydrogen/natural gas/air mixtures

Chen DONG, Qulan ZHOU, Xiaoguang ZHANG, Qinxin ZHAO, Tongmo XU, Shi’en HUI

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 4,   Pages 417-422 doi: 10.1007/s11705-010-0515-8

Abstract: Laminar flame speeds of hydrogen/natural gas/air mixtures have been measured over a full range of fuel compositions (0–100% volumetric fraction of H ) and a wide range of equivalence ratio using Bunsen burner. High sensitivity scientific CCD camera is use to capture the image of laminar flame. The reaction zone area is employed to calculate the laminar flame speed. The initial temperature and pressure of fuel air mixtures are 293 K and 1 atm. The laminar flame speeds of hydrogen/air mixture and natural gas/air mixture reach their maximum values 2.933 and 0.374 m/s when equivalence ratios equal to 1.7 and 1.1, respectively. The laminar flame speeds of hydrogen/natural gas/air mixtures rise with the increase of volumetric fraction of hydrogen. Moreover, the increase in laminar flame speed as the volumetric fraction of hydrogen increases presents an exponential increasing trend versus volumetric fraction of hydrogen. Empirical formulas to calculate the laminar flame speeds of hydrogen, natural gas, and hydrogen/natural gas mixtures are also given. Using these formulas, the laminar flame speed at different hydrogen fractions and equivalence ratios can be calculated.

Keywords： laminar flame speed     experimental study     Bunsen flame    

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and in-hospital mortality of V-V ECMO-supported patients—the ECMO quality improvement action (EQIA) study: a national cohort study in China from 2017 to 2019

Frontiers of Medicine doi: 10.1007/s11684-023-1014-x

Abstract: This cohort study was performed to explore the influence of intensive care unit (ICU) quality on in-hospitalThe study involved all V-V ECMO-supported patients in 318 of 1700 tertiary hospitals from 2017 to 2019Meanwhile, the V-V ECMO center volume was a protective factor (cutoff of ≥ 50 cases within the 3-year study

Keywords： veno-venous extracorporeal membrane oxygenation     in-hospital mortality     high-volume centers     quality control     intensive care unit capacity parameters    

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Microplastics in municipal wastewater treatment plants: a case study of Denizli/Turkey

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 8, doi: 10.1007/s11783-023-1699-8

Abstract:

● High amounts of microplastics are released to receiving media from WWTPs.

Keywords： Microplastics     Wastewater treatment plant     Removal efficiency     Daily discharge    

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Title Author Date Type Operation

Type 2 diabetes is causally associated with depression: a Mendelian randomization analysis

Liping Xuan, Zhiyun Zhao, Xu Jia, Yanan Hou, Tiange Wang, Mian Li, Jieli Lu, Yu Xu, Yuhong Chen, Lu Qi, Weiqing Wang, Yufang Bi, Min Xu

Journal Article

Bidirectional Causality Between Immunoglobulin G N-Glycosylation and Metabolic Traits: A Mendelian RandomizationStudy

Xiaoni Meng, Weijie Cao, Di Liu, Isinta Maranga Elijah, Weijia Xing, Haifeng Hou, Xizhu Xu, Manshu Song, Youxin Wang

Journal Article

Exome sequencing greatly expedites the progressive research of Mendelian diseases

Xuejun Zhang

Journal Article

Scale study of sites and pavilions for World Expo 2010

ZHOU Zhuoyan, CHEN Yi

Journal Article

Practicality study on air-powered vehicle

LIU Lin, YU Xiaoli

Journal Article

Experimental study on shear behavior of prestressed reactive powder concrete I-girders

Hui ZHENG, Zhi FANG, Bin CHEN

Journal Article

A feasibility study of the measuring accuracy and capability of wireless sensor networks in tunnel monitoring

Xiaojun LI, Zhong JI, Hehua ZHU, Chen GU

Journal Article

Wei Mingjie: Molecular Simulation Study on The Permeation Mechanism of Polyamide Reverse Osmosis Membrane

9 Jun 2022

Conference Videos

Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical

Ying Ma,Nanxue Zhang,Shi Wu,Haihui Huang,Yanpei Cao

Journal Article

Genetic study and molecular breeding for high phosphorus use efficiency in maize

Dongdong LI, Meng WANG, Xianyan KUANG, Wenxin LIU

Journal Article

Parametric study on seismic performance of self-centering reinforced concrete column with bottom-placed

Journal Article

Experimental study on the laminar flame speed of hydrogen/natural gas/air mixtures

Chen DONG, Qulan ZHOU, Xiaoguang ZHANG, Qinxin ZHAO, Tongmo XU, Shi’en HUI

Journal Article

and in-hospital mortality of V-V ECMO-supported patients—the ECMO quality improvement action (EQIA) study: a national cohort study in China from 2017 to 2019

Journal Article

Huiling Song：Policy to Mitigate Supply Constraint of Byproduct Metals for Clean Energy Technology: A Case Study

10 Jun 2022

Conference Videos

Microplastics in municipal wastewater treatment plants: a case study of Denizli/Turkey

Journal Article